Validation and Invalidation of Chemical Probes for the Human N-myristoyltransferases

On-target, cell-active chemical probes are of fundamental importance in chemical and cell biology, whereas poorly characterized probes often lead to invalid conclusions. Human N-myristoyltransferase (NMT) has attracted increasing interest as target in cancer and infectious diseases. Here we report a...

Descripción completa

Detalles Bibliográficos
Autores principales: Kallemeijn, Wouter W., Lueg, Gregor A., Faronato, Monica, Hadavizadeh, Kate, Goya Grocin, Andrea, Song, Ok-Ryul, Howell, Michael, Calado, Dinis P., Tate, Edward W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6593224/
https://www.ncbi.nlm.nih.gov/pubmed/31006618
http://dx.doi.org/10.1016/j.chembiol.2019.03.006

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6593224/
https://www.ncbi.nlm.nih.gov/pubmed/31006618
http://dx.doi.org/10.1016/j.chembiol.2019.03.006

Ejemplares similares