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Validation and Invalidation of Chemical Probes for the Human N-myristoyltransferases
On-target, cell-active chemical probes are of fundamental importance in chemical and cell biology, whereas poorly characterized probes often lead to invalid conclusions. Human N-myristoyltransferase (NMT) has attracted increasing interest as target in cancer and infectious diseases. Here we report a...
| Autores principales: | , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Cell Press
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6593224/ https://www.ncbi.nlm.nih.gov/pubmed/31006618 http://dx.doi.org/10.1016/j.chembiol.2019.03.006 |