Single-Color Digital PCR Provides High-Performance Detection of Cancer Mutations from Circulating DNA

We describe a single-color digital PCR assay that detects and quantifies cancer mutations directly from circulating DNA collected from the plasma of cancer patients. This approach relies on a double-stranded DNA intercalator dye and paired allele-specific DNA primer sets to determine an absolute cou...

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Detalles Bibliográficos
Autores principales: Wood-Bouwens, Christina, Lau, Billy T., Handy, Christine M., Lee, HoJoon, Ji, Hanlee P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Investigative Pathology 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6593258/
https://www.ncbi.nlm.nih.gov/pubmed/28818432
http://dx.doi.org/10.1016/j.jmoldx.2017.05.003

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6593258/
https://www.ncbi.nlm.nih.gov/pubmed/28818432
http://dx.doi.org/10.1016/j.jmoldx.2017.05.003

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