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CTL-Derived Exosomes Enhance the Activation of CTLs Stimulated by Low-Affinity Peptides
Cytotoxic T cells (CTLs) bind to peptides presented by MHC I (pMHC) through T cell receptors of various affinities. Low-affinity CTLs are important for the control of intracellular pathogens and cancers; however, the mechanisms by which these lower affinity CTLs are activated and maintained are not...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Frontiers Media S.A.
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6593274/ https://www.ncbi.nlm.nih.gov/pubmed/31275303 http://dx.doi.org/10.3389/fimmu.2019.01274 |