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Lipoxin-Induced Phenotypic Changes in CD115(+)LY6C(hi) Monocytes TAM Precursors Inhibits Tumor Development
During tumor development, the spleen acts as an extra-medullar reservoir of LY6C(hi) inflammatory monocytes, which can migrate toward tumor to differentiate into tumor-associated macrophage (TAMs), renewing the TAM population. In the tumor microenvironment, pro-inflammatory macrophages (M1) acquire...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6593314/ https://www.ncbi.nlm.nih.gov/pubmed/31275860 http://dx.doi.org/10.3389/fonc.2019.00540 |