Cargando…

Lipoxin-Induced Phenotypic Changes in CD115(+)LY6C(hi) Monocytes TAM Precursors Inhibits Tumor Development

During tumor development, the spleen acts as an extra-medullar reservoir of LY6C(hi) inflammatory monocytes, which can migrate toward tumor to differentiate into tumor-associated macrophage (TAMs), renewing the TAM population. In the tumor microenvironment, pro-inflammatory macrophages (M1) acquire...

Descripción completa

Detalles Bibliográficos
Autores principales: de-Brito, Natália Mesquita, da-Costa, Hayandra Cunha, Simões, Rafael Loureiro, Barja-Fidalgo, Christina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6593314/
https://www.ncbi.nlm.nih.gov/pubmed/31275860
http://dx.doi.org/10.3389/fonc.2019.00540