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On the explicit use of experimental images in high resolution cryo-EM refinement

Single particle cryogenic electron microscopy (cryo-EM) is transforming structural biology by enabling the analysis of difficult macromolecular specimens, such as membrane proteins or large complexes with flexible elements, at near atomic resolution with an accuracy close to that of X-ray crystallog...

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Detalles Bibliográficos
Autores principales: Cherfils, Jacqueline, Navaza, Jorge
Formato: Online Artículo Texto
Lenguaje:English
Publicado: F1000 Research Limited 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6593323/
https://www.ncbi.nlm.nih.gov/pubmed/31281640
http://dx.doi.org/10.12688/f1000research.19230.2