Diosbulbin B-Induced Mitochondria-Dependent Apoptosis in L-02 Hepatocytes is Regulated by Reactive Oxygen Species-Mediated Autophagy

Aim: Diosbulbin B (DB) is a major diterpenoid compound found in Dioscorea bulbifera L, a traditional medicinal herb in China. Clinical reports have confirmed that Dioscorea bulbifera L. can induce significant hepatotoxicity. In this study, we showed that DB can induce mitochondria-dependent apoptosi...

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Detalles Bibliográficos
Autores principales: Ye, Jing, Xue, Mei, Liu, Yamin, Zhu, Sirui, Li, Yu, Liu, Xiaoli, Cai, Danhong, Rui, Jia, Zhang, Liang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6593359/
https://www.ncbi.nlm.nih.gov/pubmed/31275148
http://dx.doi.org/10.3389/fphar.2019.00676

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6593359/
https://www.ncbi.nlm.nih.gov/pubmed/31275148
http://dx.doi.org/10.3389/fphar.2019.00676

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