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Two Accessory Proteins Govern MmpL3 Mycolic Acid Transport in Mycobacteria

Mycolic acids are the signature lipid of mycobacteria and constitute an important physical component of the cell wall, a target of mycobacterium-specific antibiotics and a mediator of Mycobacterium tuberculosis pathogenesis. Mycolic acids are synthesized in the cytoplasm and are thought to be transp...

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Detalles Bibliográficos
Autores principales: Fay, Allison, Czudnochowski, Nadine, Rock, Jeremy M., Johnson, Jeffrey R., Krogan, Nevan J., Rosenberg, Oren, Glickman, Michael S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6593404/
https://www.ncbi.nlm.nih.gov/pubmed/31239378
http://dx.doi.org/10.1128/mBio.00850-19