Exosomal Interferon‐Induced Transmembrane Protein 2 Transmitted to Dendritic Cells Inhibits Interferon Alpha Pathway Activation and Blocks Anti–Hepatitis B Virus Efficacy of Exogenous Interferon Alpha

The negative regulators in the interferon (IFN) signaling pathway inhibit intrahepatic immune response, resulting in suboptimal therapeutic response to IFNα treatment in chronic hepatitis B (CHB) patients. Identifying the key negative factors and elucidating the regulating mechanism are essential fo...

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Detalles Bibliográficos
Autores principales: Shi, Ying, Du, Lingyao, Lv, Duoduo, Li, Hong, Shang, Jin, Lu, Jiajie, Zhou, Lingyun, Bai, Lang, Tang, Hong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6593428/
https://www.ncbi.nlm.nih.gov/pubmed/30723923
http://dx.doi.org/10.1002/hep.30548

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6593428/
https://www.ncbi.nlm.nih.gov/pubmed/30723923
http://dx.doi.org/10.1002/hep.30548

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