B‐factor Guided Proline Substitutions in Chromobacterium violaceum Amine Transaminase: Evaluation of the Proline Rule as a Method for Enzyme Stabilization

Biocatalysis is attracting interest in the chemical industry as a sustainable alternative in large‐scale chemical transformations. However, low operational stability of naturally evolved enzymes is a challenge and major efforts are required to engineer protein stability, usually by directed evolutio...

Descripción completa

Detalles Bibliográficos
Autores principales: Land, Henrik, Campillo‐Brocal, Jonatan C., Svedendahl Humble, Maria, Berglund, Per
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Full Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6593452/
https://www.ncbi.nlm.nih.gov/pubmed/30637901
http://dx.doi.org/10.1002/cbic.201800749

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6593452/
https://www.ncbi.nlm.nih.gov/pubmed/30637901
http://dx.doi.org/10.1002/cbic.201800749

Ejemplares similares