Cytokine inflammatory threat, but not LPS one, shortens GABAergic synaptic currents in the mouse spinal cord organotypic cultures

BACKGROUND: Synaptic dysfunction, named synaptopathy, due to inflammatory status of the central nervous system (CNS) is a recognized factor potentially underlying both motor and cognitive dysfunctions in neurodegenerative diseases. To gain knowledge on the mechanistic interplay between local inflamm...

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Detalles Bibliográficos
Autores principales: Giacco, Vincenzo, Panattoni, Giulia, Medelin, Manuela, Bonechi, Elena, Aldinucci, Alessandra, Ballerini, Clara, Ballerini, Laura
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6593520/
https://www.ncbi.nlm.nih.gov/pubmed/31238967
http://dx.doi.org/10.1186/s12974-019-1519-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6593520/
https://www.ncbi.nlm.nih.gov/pubmed/31238967
http://dx.doi.org/10.1186/s12974-019-1519-z

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