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Cytokine inflammatory threat, but not LPS one, shortens GABAergic synaptic currents in the mouse spinal cord organotypic cultures
BACKGROUND: Synaptic dysfunction, named synaptopathy, due to inflammatory status of the central nervous system (CNS) is a recognized factor potentially underlying both motor and cognitive dysfunctions in neurodegenerative diseases. To gain knowledge on the mechanistic interplay between local inflamm...
Autores principales: | Giacco, Vincenzo, Panattoni, Giulia, Medelin, Manuela, Bonechi, Elena, Aldinucci, Alessandra, Ballerini, Clara, Ballerini, Laura |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6593520/ https://www.ncbi.nlm.nih.gov/pubmed/31238967 http://dx.doi.org/10.1186/s12974-019-1519-z |
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