Optimized fractionated radiotherapy with anti-PD-L1 and anti-TIGIT: a promising new combination

PURPOSE/OBJECTIVE: Radiotherapy (RT) induces an immunogenic antitumor response, but also some immunosuppressive barriers. It remains unclear how different fractionation protocols can modulate the immune microenvironment. Clinical studies are ongoing to evaluate immune checkpoint inhibitors (ICI) in...

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Detalles Bibliográficos
Autores principales: Grapin, Mathieu, Richard, Corentin, Limagne, Emeric, Boidot, Romain, Morgand, Véronique, Bertaut, Aurélie, Derangere, Valentin, Laurent, Pierre-Antoine, Thibaudin, Marion, Fumet, Jean David, Crehange, Gilles, Ghiringhelli, François, Mirjolet, Céline
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6593525/
https://www.ncbi.nlm.nih.gov/pubmed/31238970
http://dx.doi.org/10.1186/s40425-019-0634-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6593525/
https://www.ncbi.nlm.nih.gov/pubmed/31238970
http://dx.doi.org/10.1186/s40425-019-0634-9

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