Fused in sarcoma silences HIV gene transcription and maintains viral latency through suppressing AFF4 gene activation

BACKGROUND: The human immunodeficiency virus (HIV) cell reservoir is currently a main obstacle towards complete eradication of the virus. This infected pool is refractory to anti-viral therapy and harbors integrated proviruses that are transcriptionally repressed but replication competent. As transc...

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Detalles Bibliográficos
Autores principales: Krasnopolsky, Simona, Marom, Lital, Victor, Rachel A., Kuzmina, Alona, Schwartz, Jacob C., Fujinaga, Koh, Taube, Ran
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6593535/
https://www.ncbi.nlm.nih.gov/pubmed/31238957
http://dx.doi.org/10.1186/s12977-019-0478-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6593535/
https://www.ncbi.nlm.nih.gov/pubmed/31238957
http://dx.doi.org/10.1186/s12977-019-0478-x

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