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Fused in sarcoma silences HIV gene transcription and maintains viral latency through suppressing AFF4 gene activation

BACKGROUND: The human immunodeficiency virus (HIV) cell reservoir is currently a main obstacle towards complete eradication of the virus. This infected pool is refractory to anti-viral therapy and harbors integrated proviruses that are transcriptionally repressed but replication competent. As transc...

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Detalles Bibliográficos
Autores principales:	Krasnopolsky, Simona, Marom, Lital, Victor, Rachel A., Kuzmina, Alona, Schwartz, Jacob C., Fujinaga, Koh, Taube, Ran
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2019
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6593535/ https://www.ncbi.nlm.nih.gov/pubmed/31238957 http://dx.doi.org/10.1186/s12977-019-0478-x

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