Activation of cGMP/PKG/p65 signaling associated with PDE5‐Is downregulates CCL5 secretion by CD8 (+) T cells in benign prostatic hyperplasia

BACKGROUND: Benign prostatic hyperplasia (BPH) is the most common urological disease in elderly men, but the underlying pathophysiological mechanisms are complex and not fully understood. Phosphodiesterase type 5 inhibitors (PDE5‐Is) used to treat BPH could upregulate the cyclic guanosine monophosph...

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Detalles Bibliográficos
Autores principales: Jin, Song, Xiang, Peng, Liu, Jie, Yang, Yang, Hu, Shuai, Sheng, Jindong, He, Qun, Yu, Wei, Han, Wenke, Jin, Jie, Peng, Jing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6593656/
https://www.ncbi.nlm.nih.gov/pubmed/30958912
http://dx.doi.org/10.1002/pros.23801

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6593656/
https://www.ncbi.nlm.nih.gov/pubmed/30958912
http://dx.doi.org/10.1002/pros.23801

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