N‐methyl‐D‐aspartate receptor dysfunction by unmutated human antibodies against the NR1 subunit

Anti–N‐methyl‐D‐aspartate receptor (NMDAR) encephalitis is the most common autoimmune encephalitis related to autoantibody‐mediated synaptic dysfunction. Cerebrospinal fluid–derived human monoclonal NR1 autoantibodies showed low numbers of somatic hypermutations or were unmutated. These unexpected g...

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Detalles Bibliográficos
Autores principales: Wenke, Nina Kerstin, Kreye, Jakob, Andrzejak, Ewa, van Casteren, Adriana, Leubner, Jonas, Murgueitio, Manuela S., Reincke, S. Momsen, Secker, Christopher, Schmidl, Lars, Geis, Christian, Ackermann, Frauke, Nikolaus, Marc, Garner, Craig C., Wardemann, Hedda, Wolber, Gerhard, Prüss, Harald
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2019
Materias:
Brief Communications
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6593665/
https://www.ncbi.nlm.nih.gov/pubmed/30843274
http://dx.doi.org/10.1002/ana.25460

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6593665/
https://www.ncbi.nlm.nih.gov/pubmed/30843274
http://dx.doi.org/10.1002/ana.25460

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