Prolonged low-dose infusion for gemcitabine: a systematic review

BACKGROUND: The present standard dose of gemcitabine (Gem), a pyrimidine antimetabolite, is 1,000–1,250 mg/m(2), and the infusion time is 30 min. However, pharmacological studies have demonstrated that Gem with prolonged infusion could attain a better accumulation rate of Gem triphosphate (active me...

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Detalles Bibliográficos
Autores principales: Zhao, Dehua, Chen, Jing, Chu, Mingming, Wang, Jisheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2019
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6593688/
https://www.ncbi.nlm.nih.gov/pubmed/31417283
http://dx.doi.org/10.2147/OTT.S210117

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6593688/
https://www.ncbi.nlm.nih.gov/pubmed/31417283
http://dx.doi.org/10.2147/OTT.S210117

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