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α‐Synuclein real‐time quaking‐induced conversion in the cerebrospinal fluid of uncertain cases of parkinsonism

A reliable biomarker is needed for accurate and early differentiation between Parkinson disease and the various forms of atypical parkinsonism. We used a novel real‐time quaking‐induced conversion (RT‐QuIC) assay to detect α‐synuclein (α‐syn) aggregates in cerebrospinal fluid (CSF) of 118 patients w...

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Detalles Bibliográficos
Autores principales: van Rumund, Anouke, Green, Alison J. E., Fairfoul, Graham, Esselink, Rianne A. J., Bloem, Bastiaan R., Verbeek, Marcel M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6593725/
https://www.ncbi.nlm.nih.gov/pubmed/30801759
http://dx.doi.org/10.1002/ana.25447