Preclinical Assessment of Leptin Transport into the Cerebrospinal Fluid in Diet‐Induced Obese Minipigs

OBJECTIVE: A minipig model was employed to explore the changes in endogenous leptin transport into the central nervous system and in hypothalamic sensitivity to exogenous leptin when individuals are placed on high‐fat diet (HFD) compared with standard diet. METHODS: Serum and cerebrospinal fluid (CS...

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Detalles Bibliográficos
Autores principales: Chmielewski, Alexandra, Hubert, Thomas, Descamps, Amandine, Mazur, Daniele, Daoudi, Mehdi, Ciofi, Philippe, Fontaine, Christian, Caiazzo, Robert, Pattou, François, Prevot, Vincent, Pigeyre, Marie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6593767/
https://www.ncbi.nlm.nih.gov/pubmed/31006983
http://dx.doi.org/10.1002/oby.22465

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6593767/
https://www.ncbi.nlm.nih.gov/pubmed/31006983
http://dx.doi.org/10.1002/oby.22465

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