Metabolism, Excretion, and Pharmacokinetics of [(14)C]‐Cefiderocol (S‐649266), a Siderophore Cephalosporin, in Healthy Subjects Following Intravenous Administration

The objectives of this study were to characterize the concentration‐time profiles of total radioactivity equivalent and unchanged cefiderocol, the route(s) of elimination and mass balance, and safety of cefiderocol after intravenous administration of a single 1000‐mg (100 μCi) dose of [(14)C]‐cefide...

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Detalles Bibliográficos
Autores principales: Miyazaki, Shiro, Katsube, Takayuki, Shen, Helen, Tomek, Charles, Narukawa, Yukitoshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Pharmacokinetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6593826/
https://www.ncbi.nlm.nih.gov/pubmed/30730562
http://dx.doi.org/10.1002/jcph.1386

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6593826/
https://www.ncbi.nlm.nih.gov/pubmed/30730562
http://dx.doi.org/10.1002/jcph.1386

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