Plasminogen activator inhibitor‐1 augments damage by impairing fibrinolysis after traumatic brain injury

OBJECTIVE: Plasminogen activator inhibitor‐1 (PAI‐1) is the key endogenous inhibitor of fibrinolysis, and enhances clot formation after injury. In traumatic brain injury, dysregulation of fibrinolysis may lead to sustained microthrombosis and accelerated lesion expansion. In the present study, we hy...

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Detalles Bibliográficos
Autores principales: Griemert, Eva‐Verena, Schwarzmaier, Susanne M., Hummel, Regina, Gölz, Christina, Yang, Dong, Neuhaus, Winfried, Burek, Malgorzata, Förster, Carola Y., Petkovic, Ivan, Trabold, Raimund, Plesnila, Nikolaus, Engelhard, Kristin, Schäfer, Michael K., Thal, Serge C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Ltd 2019
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6593843/
https://www.ncbi.nlm.nih.gov/pubmed/30843275
http://dx.doi.org/10.1002/ana.25458

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6593843/
https://www.ncbi.nlm.nih.gov/pubmed/30843275
http://dx.doi.org/10.1002/ana.25458

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