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RN181 is a tumour suppressor in gastric cancer by regulation of the ERK/MAPK–cyclin D1/CDK4 pathway

RN181, a RING finger domain‐containing protein, is an E3 ubiquitin ligase. However, its biological function and clinical significance in cancer biology are obscure. Here, we report that RN181 expression is significantly down‐regulated in 165 tumour tissues of gastric carcinoma (GC) versus adjacent n...

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Detalles Bibliográficos
Autores principales: Wang, Suihai, Wang, Xiaobo, Gao, Yanjun, Peng, Yingxia, Dong, Ningning, Xie, Qian, Zhang, Xian, Wu, Yingsong, Li, Ming, Li, Ji‐Liang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Ltd 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6593865/
https://www.ncbi.nlm.nih.gov/pubmed/30714150
http://dx.doi.org/10.1002/path.5246