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Natural disease history of the D2-mdx mouse model for Duchenne muscular dystrophy

The C57BL/10ScSn-Dmd(mdx)/J (BL10-mdx) mouse has been the most commonly used model for Duchenne muscular dystrophy (DMD) for decades. Their muscle dysfunction and pathology is, however, less severe than in patients with DMD, which complicates preclinical studies. Recent discoveries indicate that dis...

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Detalles Bibliográficos
Autores principales: van Putten, Maaike, Putker, Kayleigh, Overzier, Maurice, Adamzek, W. A., Pasteuning-Vuhman, Svetlana, Plomp, Jaap J., Aartsma-Rus, Annemieke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Federation of American Societies for Experimental Biology 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6593893/
https://www.ncbi.nlm.nih.gov/pubmed/30933664
http://dx.doi.org/10.1096/fj.201802488R