Haploinsufficiency of UNC13D increases the risk of lymphoma

BACKGROUND: Experimental models have demonstrated that immune surveillance by cytotoxic lymphocytes can protect from spontaneous neoplasms and cancer. In humans, defective lymphocyte cytotoxicity is associated with the development of hemophagocytic lymphohistiocytosis, a hyperinflammatory syndrome....

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Detalles Bibliográficos
Autores principales: Löfstedt, Alexandra, Ahlm, Clas, Tesi, Bianca, Bergdahl, Ingvar A., Nordenskjöld, Magnus, Bryceson, Yenan T., Henter, Jan‐Inge, Meeths, Marie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6593970/
https://www.ncbi.nlm.nih.gov/pubmed/30758854
http://dx.doi.org/10.1002/cncr.32011

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6593970/
https://www.ncbi.nlm.nih.gov/pubmed/30758854
http://dx.doi.org/10.1002/cncr.32011

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