Inhibition of MAPK/ERK pathway promotes oligodendrocytes generation and recovery of demyelinating diseases

Oligodendrocytes (OLs) are the myelinating glia of the central nervous system. Injury to OLs causes myelin loss. In demyelinating diseases, such as multiple sclerosis, the remyelination is hindered principally due to a failure of the oligodendrocyte precursor cells (OPCs) to differentiate into matur...

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Detalles Bibliográficos
Autores principales: Suo, Na, Guo, Yu‐e, He, Bingqing, Gu, Haifeng, Xie, Xin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2019
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6593996/
https://www.ncbi.nlm.nih.gov/pubmed/30815939
http://dx.doi.org/10.1002/glia.23606

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6593996/
https://www.ncbi.nlm.nih.gov/pubmed/30815939
http://dx.doi.org/10.1002/glia.23606

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