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Tumor suppressor KIF1Bβ regulates mitochondrial apoptosis in collaboration with YME1L1

KIF1Bβ, a member of the kinesin superfamily of motor proteins, is a haploinsufficient tumor suppressor mapped to chromosome 1p36.2, which is frequently deleted in neural crest–derived tumors, including neuroblastoma and pheochromocytoma. While KIF1Bβ acts downstream of the nerve growth factor (NGF)...

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Detalles Bibliográficos
Autores principales: Ando, Koji, Yokochi, Tomoki, Mukai, Akira, Wei, Gao, Li, Yuanyuan, Kramer, Sonja, Ozaki, Toshinori, Maehara, Yoshihiko, Nakagawara, Akira
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6593999/
https://www.ncbi.nlm.nih.gov/pubmed/30859632
http://dx.doi.org/10.1002/mc.22997