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Infiltrating CD4+ T cells attenuate chemotherapy sensitivity in prostate cancer via CCL5 signaling

BACKGROUND: Chemotherapy with Docetaxel (Doc) is efficient in a subset of prostate cancer (PCa) cases; however, most patients ultimately develop resistance to Docetaxel. The tumor immune microenvironment and secreted cytokines play a substantial role in development of resistance to chemotherapy. Our...

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Detalles Bibliográficos
Autores principales: Xiang, Peng, Jin, Song, Yang, Yang, Sheng, Jindong, He, Qun, Song, Yi, Yu, Wei, Hu, Shuai, Jin, Jie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6594129/
https://www.ncbi.nlm.nih.gov/pubmed/31018021
http://dx.doi.org/10.1002/pros.23810