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Early Electrophysiological Disintegration of Hippocampal Neural Networks in a Novel Locus Coeruleus Tau-Seeding Mouse Model of Alzheimer's Disease

Alzheimer's disease (AD) is a progressive, neurodegenerative disease characterized by loss of synapses and disrupted functional connectivity (FC) across different brain regions. Early in AD progression, tau pathology is found in the locus coeruleus (LC) prior to amyloid-induced exacerbation of...

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Detalles Bibliográficos
Autores principales: Ahnaou, A., Walsh, C., Manyakov, N. V., Youssef, S. A., Drinkenburg, W. H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6594257/
https://www.ncbi.nlm.nih.gov/pubmed/31285742
http://dx.doi.org/10.1155/2019/6981268