High Thymic Output of Effector CD4(+) Cells May Lead to a Treg : T Effector Imbalance in the Periphery in NOD Mice

Regulatory T cells (Tregs) play a critical role in controlling autoreactive T cells, and quantitative and/or qualitative deficiencies in Tregs are associated with autoimmune diseases, including type 1 diabetes (T1D), in both humans and mice. Both the incidence of T1D and percentages of peripheral Tr...

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Detalles Bibliográficos
Autores principales: Zhao, Yuan, Alard, Pascale, Kosiewicz, Michele M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6594269/
https://www.ncbi.nlm.nih.gov/pubmed/31281853
http://dx.doi.org/10.1155/2019/8785263

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6594269/
https://www.ncbi.nlm.nih.gov/pubmed/31281853
http://dx.doi.org/10.1155/2019/8785263

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