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High Thymic Output of Effector CD4(+) Cells May Lead to a Treg : T Effector Imbalance in the Periphery in NOD Mice
Regulatory T cells (Tregs) play a critical role in controlling autoreactive T cells, and quantitative and/or qualitative deficiencies in Tregs are associated with autoimmune diseases, including type 1 diabetes (T1D), in both humans and mice. Both the incidence of T1D and percentages of peripheral Tr...
Autores principales: | Zhao, Yuan, Alard, Pascale, Kosiewicz, Michele M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6594269/ https://www.ncbi.nlm.nih.gov/pubmed/31281853 http://dx.doi.org/10.1155/2019/8785263 |
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