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STAT Family Protein Expression and Phosphorylation State during moDC Development Is Altered by Platinum-Based Chemotherapeutics

The STAT signaling pathway is important in dendritic cell (DC) development and function. Tumor cells can induce STAT signaling, thereby inhibiting DC maturation and immunostimulatory functions, leading to hampered efficacy of DC-based immunotherapies. Platinum-based chemotherapeutics can inhibit STA...

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Detalles Bibliográficos
Autores principales: de Haas, Nienke, de Koning, Coco, di Blasio, Stefania, Flórez-Grau, Georgina, de Vries, I. Jolanda M., Hato, Stanleyson V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6594321/
https://www.ncbi.nlm.nih.gov/pubmed/31309123
http://dx.doi.org/10.1155/2019/7458238