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Phenotypic Plasticity of Invasive Edge Glioma Stem-like Cells in Response to Ionizing Radiation

Unresectable glioblastoma (GBM) cells in the invading tumor edge can act as seeds for recurrence. The molecular and phenotypic properties of these cells remain elusive. Here, we report that the invading edge and tumor core have two distinct types of glioma stem-like cells (GSCs) that resemble proneu...

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Detalles Bibliográficos
Autores principales: Minata, Mutsuko, Audia, Alessandra, Shi, Junfeng, Lu, Songjian, Bernstock, Joshua, Pavlyukov, Marat S., Das, Arvid, Kim, Sung-Hak, Shin, Yong Jae, Lee, Yeri, Koo, Harim, Snigdha, Kirti, Waghmare, Indrayani, Guo, Xing, Mohyeldin, Ahmed, Gallego-Perez, Daniel, Wang, Jia, Chen, Dongquan, Cheng, Peng, Mukheef, Farah, Contreras, Minerva, Reyes, Joel F., Vaillant, Brian, Sulman, Erik P., Cheng, Shi-Yuan, Markert, James M., Tannous, Bakhos A., Lu, Xinghua, Kango-Singh, Madhuri, Lee, L. James, Nam, Do-Hyun, Nakano, Ichiro, Bhat, Krishna P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6594377/
https://www.ncbi.nlm.nih.gov/pubmed/30759398
http://dx.doi.org/10.1016/j.celrep.2019.01.076