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Dissociation of membrane–chromatin contacts is required for proper chromosome segregation in mitosis
The nuclear envelope (NE) aids in organizing the interphase genome by tethering chromatin to the nuclear periphery. During mitotic entry, NE–chromatin contacts are broken. Here, we report on the consequences of impaired NE removal from chromatin for cell division of human cells. Using a membrane–chr...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The American Society for Cell Biology
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6594442/ https://www.ncbi.nlm.nih.gov/pubmed/30586323 http://dx.doi.org/10.1091/mbc.E18-10-0609 |