Cargando…

Dissociation of membrane–chromatin contacts is required for proper chromosome segregation in mitosis

The nuclear envelope (NE) aids in organizing the interphase genome by tethering chromatin to the nuclear periphery. During mitotic entry, NE–chromatin contacts are broken. Here, we report on the consequences of impaired NE removal from chromatin for cell division of human cells. Using a membrane–chr...

Descripción completa

Detalles Bibliográficos
Autores principales: Champion, Lysie, Pawar, Sumit, Luithle, Naemi, Ungricht, Rosemarie, Kutay, Ulrike
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6594442/
https://www.ncbi.nlm.nih.gov/pubmed/30586323
http://dx.doi.org/10.1091/mbc.E18-10-0609