Early ctDNA dynamics as a surrogate for progression-free survival in advanced breast cancer in the BEECH trial

BACKGROUND: Dynamic changes in circulating tumour DNA (ctDNA) levels may predict long-term outcome. We utilised samples from a phase I/II randomised trial (BEECH) to assess ctDNA dynamics as a surrogate for progression-free survival (PFS) and early predictor of drug efficacy. PATIENTS AND METHODS: P...

Descripción completa

Detalles Bibliográficos
Autores principales: Hrebien, S, Citi, V, Garcia-Murillas, I, Cutts, R, Fenwick, K, Kozarewa, I, McEwen, R, Ratnayake, J, Maudsley, R, Carr, T H, de Bruin, E C, Schiavon, G, Oliveira, M, Turner, N
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6594458/
https://www.ncbi.nlm.nih.gov/pubmed/30860573
http://dx.doi.org/10.1093/annonc/mdz085

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6594458/
https://www.ncbi.nlm.nih.gov/pubmed/30860573
http://dx.doi.org/10.1093/annonc/mdz085

Ejemplares similares