PLEKHA4/kramer Attenuates Dishevelled Ubiquitination to Modulate Wnt and Planar Cell Polarity Signaling

Wnt signaling pathways direct key physiological decisions in development. Here, we establish a role for a pleckstrin homology domain-containing protein, PLEKHA4, as a modulator of signaling strength in Wnt receiving cells. PLEKHA4 oligomerizes into clusters at PI(4,5)P(2)-rich regions of the plasma...

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Detalles Bibliográficos
Autores principales: Shah, Adnan Shami, Batrouni, Alex G., Kim, Dongsung, Punyala, Amith, Cao, Wendy, Han, Chun, Goldberg, Michael L., Smolka, Marcus B., Baskin, Jeremy M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6594551/
https://www.ncbi.nlm.nih.gov/pubmed/31091453
http://dx.doi.org/10.1016/j.celrep.2019.04.060

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6594551/
https://www.ncbi.nlm.nih.gov/pubmed/31091453
http://dx.doi.org/10.1016/j.celrep.2019.04.060

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