Cargando…
Perineuronal Net Formation during the Critical Period for Neuronal Maturation in the Hypothalamic Arcuate Nucleus
In leptin-deficient ob/ob mice, obesity and diabetes are associated with abnormal development of neurocircuits in the hypothalamic arcuate nucleus (ARC)(1), a critical brain area for energy and glucose homeostasis(2,3). As this developmental defect can be remedied by systemic leptin administration,...
Autores principales: | , , , , , , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6594569/ https://www.ncbi.nlm.nih.gov/pubmed/31245789 http://dx.doi.org/10.1038/s42255-018-0029-0 |