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Predicting gastrointestinal drug effects using contextualized metabolic models
Gastrointestinal side effects are among the most common classes of adverse reactions associated with orally absorbed drugs. These effects decrease patient compliance with the treatment and induce undesirable physiological effects. The prediction of drug action on the gut wall based on in vitro data...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2019
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6594586/ https://www.ncbi.nlm.nih.gov/pubmed/31242176 http://dx.doi.org/10.1371/journal.pcbi.1007100 |