Cargando…

A Flp-SUMO hybrid recombinase reveals multi-layered copy number control of a selfish DNA element through post-translational modification

Mechanisms for highly efficient chromosome-associated equal segregation, and for maintenance of steady state copy number, are at the heart of the evolutionary success of the 2-micron plasmid as a stable multi-copy extra-chromosomal selfish DNA element present in the yeast nucleus. The Flp site-speci...

Descripción completa

Detalles Bibliográficos
Autores principales: Ma, Chien-Hui, Su, Bo-Yu, Maciaszek, Anna, Fan, Hsiu-Fang, Guga, Piotr, Jayaram, Makkuni
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6594588/
https://www.ncbi.nlm.nih.gov/pubmed/31242181
http://dx.doi.org/10.1371/journal.pgen.1008193