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A Flp-SUMO hybrid recombinase reveals multi-layered copy number control of a selfish DNA element through post-translational modification
Mechanisms for highly efficient chromosome-associated equal segregation, and for maintenance of steady state copy number, are at the heart of the evolutionary success of the 2-micron plasmid as a stable multi-copy extra-chromosomal selfish DNA element present in the yeast nucleus. The Flp site-speci...
Autores principales: | Ma, Chien-Hui, Su, Bo-Yu, Maciaszek, Anna, Fan, Hsiu-Fang, Guga, Piotr, Jayaram, Makkuni |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6594588/ https://www.ncbi.nlm.nih.gov/pubmed/31242181 http://dx.doi.org/10.1371/journal.pgen.1008193 |
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