SIRT1 deficiency interferes with membrane resealing after cell membrane injury

Activation of SIRT1, an NAD(+)-dependent protein deacetylase, ameliorates muscular pathophysiology of δ-sarcoglycan-deficient TO-2 hamsters and dystrophin-deficient mdx mice. We found that SIRT1 was highly expressed beneath the cellular membranes of muscle cells. To elucidate functional roles of SIR...

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Detalles Bibliográficos
Autores principales: Fujiwara, Daisuke, Iwahara, Naotoshi, Sebori, Rio, Hosoda, Ryusuke, Shimohama, Shun, Kuno, Atsushi, Horio, Yoshiyuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6594621/
https://www.ncbi.nlm.nih.gov/pubmed/31242212
http://dx.doi.org/10.1371/journal.pone.0218329

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6594621/
https://www.ncbi.nlm.nih.gov/pubmed/31242212
http://dx.doi.org/10.1371/journal.pone.0218329

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