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SIRT1 deficiency interferes with membrane resealing after cell membrane injury
Activation of SIRT1, an NAD(+)-dependent protein deacetylase, ameliorates muscular pathophysiology of δ-sarcoglycan-deficient TO-2 hamsters and dystrophin-deficient mdx mice. We found that SIRT1 was highly expressed beneath the cellular membranes of muscle cells. To elucidate functional roles of SIR...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6594621/ https://www.ncbi.nlm.nih.gov/pubmed/31242212 http://dx.doi.org/10.1371/journal.pone.0218329 |