Ticagrelor induces paraoxonase-1 (PON1) and better protects hypercholesterolemic mice against atherosclerosis compared to clopidogrel

Ticagrelor (TIC), a P2Y purinoceptor 12 (P2Y(12))-receptor antagonist, has been widely used to treat patients with acute coronary syndrome. Although animal studies suggest that TIC protects against atherosclerosis, it remains unknown whether it does so through its potent platelet inhibition or throu...

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Detalles Bibliográficos
Autores principales: Halim, Hasseri, Pinkaew, Decha, Chunhacha, Preedakorn, Sinthujaroen, Patuma, Thiagarajan, Perumal, Fujise, Ken
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6594647/
https://www.ncbi.nlm.nih.gov/pubmed/31242230
http://dx.doi.org/10.1371/journal.pone.0218934

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6594647/
https://www.ncbi.nlm.nih.gov/pubmed/31242230
http://dx.doi.org/10.1371/journal.pone.0218934

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