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GPIHBP1 expression in gliomas promotes utilization of lipoprotein-derived nutrients
GPIHBP1, a GPI-anchored protein of capillary endothelial cells, binds lipoprotein lipase (LPL) within the subendothelial spaces and shuttles it to the capillary lumen. GPIHBP1-bound LPL is essential for the margination of triglyceride-rich lipoproteins (TRLs) along capillaries, allowing the lipolyti...
Autores principales: | Hu, Xuchen, Matsumoto, Ken, Jung, Rachel S, Weston, Thomas A, Heizer, Patrick J, He, Cuiwen, Sandoval, Norma P, Allan, Christopher M, Tu, Yiping, Vinters, Harry V, Liau, Linda M, Ellison, Rochelle M, Morales, Jazmin E, Baufeld, Lynn J, Bayley, Nicholas A, He, Liqun, Betsholtz, Christer, Beigneux, Anne P, Nathanson, David A, Gerhardt, Holger, Young, Stephen G, Fong, Loren G, Jiang, Haibo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6594755/ https://www.ncbi.nlm.nih.gov/pubmed/31169500 http://dx.doi.org/10.7554/eLife.47178 |
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