Long non-coding RNA MEG3 promotes fibrosis and inflammatory response in diabetic nephropathy via miR-181a/Egr-1/TLR4 axis

Long non-coding RNAs (lncRNAs) play vital roles in diabetic nephropathy (DN). This research aimed to study the potential role and underlying molecular mechanisms of long non-coding RNA MEG3 in DN. We found that MEG3 was upregulated in DN in vivo and in vitro and could enhance cell fibrosis and infla...

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Detalles Bibliográficos
Autores principales: Zha, Fangfang, Qu, Xiaolu, Tang, Bo, Li, Ji, Wang, Yakun, Zheng, PengXi, Ji, Tingting, Zhu, Chun, Bai, Shoujun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2019
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6594792/
https://www.ncbi.nlm.nih.gov/pubmed/31195367
http://dx.doi.org/10.18632/aging.102011

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6594792/
https://www.ncbi.nlm.nih.gov/pubmed/31195367
http://dx.doi.org/10.18632/aging.102011

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