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Long non-coding RNA MEG3 promotes fibrosis and inflammatory response in diabetic nephropathy via miR-181a/Egr-1/TLR4 axis
Long non-coding RNAs (lncRNAs) play vital roles in diabetic nephropathy (DN). This research aimed to study the potential role and underlying molecular mechanisms of long non-coding RNA MEG3 in DN. We found that MEG3 was upregulated in DN in vivo and in vitro and could enhance cell fibrosis and infla...
Autores principales: | Zha, Fangfang, Qu, Xiaolu, Tang, Bo, Li, Ji, Wang, Yakun, Zheng, PengXi, Ji, Tingting, Zhu, Chun, Bai, Shoujun |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6594792/ https://www.ncbi.nlm.nih.gov/pubmed/31195367 http://dx.doi.org/10.18632/aging.102011 |
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