α-Ketoglutarate inhibits autophagy

The metabolite α-ketoglutarate is membrane-impermeable, meaning that it is usually added to cells in the form of esters such as dimethyl −ketoglutarate (DMKG), trifluoromethylbenzyl α-ketoglutarate (TFMKG) and octyl α-ketoglutarate (O-KG). Once these compounds cross the plasma membrane, they are hyd...

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Detalles Bibliográficos
Autores principales: Baracco, Elisa Elena, Castoldi, Francesca, Durand, Sylvère, Enot, David P., Tadic, Jelena, Kainz, Katharina, Madeo, Frank, Chery, Alexis, Izzo, Valentina, Maiuri, Maria Chiara, Pietrocola, Federico, Kroemer, Guido
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2019
Materias:
Priority Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6594794/
https://www.ncbi.nlm.nih.gov/pubmed/31173576
http://dx.doi.org/10.18632/aging.102001

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6594794/
https://www.ncbi.nlm.nih.gov/pubmed/31173576
http://dx.doi.org/10.18632/aging.102001

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