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α-Ketoglutarate inhibits autophagy
The metabolite α-ketoglutarate is membrane-impermeable, meaning that it is usually added to cells in the form of esters such as dimethyl −ketoglutarate (DMKG), trifluoromethylbenzyl α-ketoglutarate (TFMKG) and octyl α-ketoglutarate (O-KG). Once these compounds cross the plasma membrane, they are hyd...
Autores principales: | Baracco, Elisa Elena, Castoldi, Francesca, Durand, Sylvère, Enot, David P., Tadic, Jelena, Kainz, Katharina, Madeo, Frank, Chery, Alexis, Izzo, Valentina, Maiuri, Maria Chiara, Pietrocola, Federico, Kroemer, Guido |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6594794/ https://www.ncbi.nlm.nih.gov/pubmed/31173576 http://dx.doi.org/10.18632/aging.102001 |
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