Nectandrin B-mediated activation of the AMPK pathway prevents cellular senescence in human diploid fibroblasts by reducing intracellular ROS levels

Nectandrin B (NecB) is a bioactive lignan compound isolated from Myristica fragrans (nutmeg), which functions as an activator of AMP-activated protein kinase (AMPK). Because we recently found that treatment with NecB increased the cell viability of old human diploid fibroblasts (HDFs), the underlyin...

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Detalles Bibliográficos
Autores principales: Jang, Hyun-Jin, Yang, Kyeong Eun, Oh, Won Keun, Lee, Song-I, Hwang, In-Hu, Ban, Kyung-Tae, Yoo, Hwa-Seung, Choi, Jong-Soon, Yeo, Eui-Ju, Jang, Ik-Soon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2019
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6594796/
https://www.ncbi.nlm.nih.gov/pubmed/31199782
http://dx.doi.org/10.18632/aging.102013

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6594796/
https://www.ncbi.nlm.nih.gov/pubmed/31199782
http://dx.doi.org/10.18632/aging.102013

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